Tšireletso ea Tšireletso eaMicroecology ea Letlaloka Letlalo
Litšoelesa tsa sebaceous li hlahisa lipids, tse hlahisoang ke likokoana-hloko ho etsa filimi ea emulsified lipid. Lifilimi tsena tsa lipid li na le li-acid tse sa lefelloeng tsa mafura, tse tsejoang hape e le lifilimi tsa acid, tse ka fokotsang lintho tsa alkaline tse silafetseng letlalong le ho thibela libaktheria tsa kantle ho naha (libaktheria tse fetang). , li-fungus le likokoana-hloko tse ling tsa pathogenic lia hōla, kahoo mosebetsi oa pele oa limela tse tloaelehileng tsa letlalo ke phello ea bohlokoa ea tšireletso.
Ho hlasela ha letlalo le li-appendages, ho kopanyelletsa le litšoelesa tsa mofufutso (litšoelesa tsa mofufutso), litšoelesa tsa sebaceous, le mela ea moriri, li na le limela tsa tsona tse ikhethang. Litšoelesa tsa sebaceous li kopanya liphahlo tsa moriri ho etsa karolo ea follicular sebaceous unit, e hlahisang ntho e ngata ea lipid e bitsoang sebum. Sebum ke filimi e sireletsang ea hydrophobic e sireletsang le ho tlotsa letlalo le moriri 'me e sebetsa e le thebe ea antibacterial. Litšoelesa tsa sebaceous li batla li le hypoxic, li tšehetsa kholo ea libaktheria tsa anaerobic tsa facultative joalo kaP. li-acne, e nang le P. acnes lipase e nyenyefatsang sebum, hydrolyzes triglycerides in sebum, le ho lokolla mafura a mahala a acid. Libaktheria li ka khomarela li-acid tsena tse sa lefelloeng, tse thusang ho hlalosa bokolone ba litšoelesa tsa sebaceous ka P. acnes, 'me li-acid tsena tse sa lefelloeng tsa mafura li boetse li tlatsetsa ho acidity ea letlalo la letlalo (pH ea 5). Libaktheria tse ngata tse tloaelehileng tsa pathogenic, tse kang Staphylococcus aureus le Streptococcus pyogenes, li thibetsoe sebakeng se nang le asiti 'me kahoo li loketse kholo ea coagulase-negative staphylococci le baktheria ea coryneform. Leha ho le joalo, ho koaleha ha letlalo ho fella ka keketseho ea pH e tla thusa ho hōla ha S. aureus le S. pyogenes. Kaha batho ba hlahisa li-sebum triglycerides tse ngata ho feta liphoofolo tse ling, P. acnes e ngata e laola letlalo la motho.
Nako ea poso: Jun-27-2022
