Hormone e fokotseha ka lilemo, ho kenyelletsa estrogen, testosterone, dehydroepiandrosterone sulfate, le hormone ea ho hōla. Litholoana tsa li-hormone letlalong li ngata, ho kenyelletsa le ho eketseha ha collagen, ho eketseha ha letlalo le botenya, le ho ntlafatsa metsi a letlalo. Har'a bona, tšusumetso ea estrogen e totobetse haholoanyane, empa mochine oa tšusumetso ea eona liseleng o ntse o sa utloisisoe hantle. Phello ea estrogen letlalong e bonahala haholo-holo ka keratinocyte ea epidermis, fibroblasts le melanocytes ea dermis, hammoho le lisele tsa moriri oa moriri le litšoelesa tsa sebaceous. Ha matla a basali a ho hlahisa estrogen a fokotseha, ho tsofala ha letlalo hoa potlaka. Ho haella ha hormone estradiol ho fokotsa ts'ebetso ea karolo ea basal ea epidermis le ho fokotsa motsoako oa li-collagen le li-elastic fibers, tseo kaofela li leng bohlokoa bakeng sa ho boloka letlalo le letle. Ho fokotseha ha maemo a estrogen a postmenopausal ha ho lebise feela ho fokotseha ha letlalo la collagen, empa hape metabolism ea lisele tsa dermal e angoa ke maemo a tlaase a estrogen a postmenopausal, 'me liphetoho tsena li ka fetoloa ka potlako ka tšebeliso ea lihlooho tsa estrogen. Liteko li netefalitse hore estrogen ea topical estrogen e ka eketsa collagen, ea boloka botenya ba letlalo, 'me ea boloka mongobo oa letlalo le ts'ebetso ea thibelo ea stratum corneum ka ho eketsa acidic glycosaminoglycans le hyaluronic acid, e le hore letlalo le boloke elasticity e ntle. Hoa hlokomeleha hore ho fokotseha ha tšebetso ea 'mele ea endocrine le eona ke e' ngoe ea lintlha tsa bohlokoa tse susumetsang mokhoa oa ho tsofala ha letlalo.
Ho fokotseha ha secretion ho tsoa ho pituitary, adrenal, le gonads ho kenya letsoho liphetohong tse hlahang 'meleng le letlalong la phenotype le mekhoa ea boitšoaro e amanang le botsofali. Maemo a serum a 17β-estradiol, dehydroepiandrosterone, progesterone, hormone ea ho hōla, le hormone ea bona e tlaase ea hormone insulin growth factor (IGF) -Ke fokotseha ka lilemo. Leha ho le joalo, litekanyetso tsa hormone ea ho hōla le IGF-I ka serum ea banna li fokotsehile haholo, 'me ho fokotseha ha maemo a li-hormone ho batho ba bang ho ka etsahala nakong ea khale. Li-hormone li ka ama sebopeho le tšebetso ea letlalo, ho kenella ha letlalo, ho fola, cortical lipogenesis le metabolism ea letlalo. Kalafo ya go buša estrogen e ka thibela go kgaotša ga modikologo wa go hlapa ga basadi le go tsofala ga letlalo.
——”Skin Epiphysiology” Yinmao Dong, Laiji Ma, Chemical Industry Press
Ka hona, ha re ntse re hōla, tlhokomelo ea rona ho maemo a letlalo e lokela ho eketseha butle-butle. Re ka sebelisa litsebi tse linglisebelisoa tsa ho hlahloba letlaloho shebella le ho bolela esale pele boemo ba letlalo, ho bolela esale pele mathata a letlalo pele, le ho sebetsana le bona ka mafolofolo.
Nako ea poso: Jan-05-2023
