Hormone e fokotseha ha lilemo li ntse li feta, ho kenyeletsoa estrogen, testosterone, dehydroepiandrosterone sulfate, le hormone ea kholo. Litlamorao tsa lihormone letlalong li ngata, ho kenyeletsoa le keketseho ea collagen, keketseho ea botenya ba letlalo, le ntlafatso ea metsi a letlalo. Har'a tsona, tšusumetso ea estrogen e totobetse haholoanyane, empa mokhoa oa tšusumetso ea eona liseleng o ntse o sa utloisisoe hantle. Tšusumetso ea estrogen letlalong e bonoa haholo-holo ka keratinocytes ea epidermis, fibroblasts le melanocytes ea dermis, hammoho le lisele tsa follicle ea moriri le litšoelesa tsa sebaceous. Ha bokhoni ba basali ba ho hlahisa estrogen bo fokotseha, ts'ebetso ea ho tsofala ha letlalo ea potlaka. Khaello ea hormone estradiol e fokotsa ts'ebetso ea lera la basal la epidermis mme e fokotsa tlhahiso ea collagen le likhoele tse tenyetsehang, tseo kaofela li leng tsa bohlokoa bakeng sa ho boloka elasticity e ntle ea letlalo. Ho theoha ha maemo a estrogen kamora ho khaotsa ho ilela khoeli ha ho lebise feela phokotsong ea maemo a collagen ea letlalo, empa hape metabolism ea lisele tsa letlalo e angoa ke maemo a tlase a estrogen kamora ho ilela khoeli, 'me liphetoho tsena li ka fetoloa kapele ka ho sebelisoa ha estrogen ka ntle ho letlalo. Liteko li tiisitse hore estrogen ea basali e ka eketsa collagen, ea boloka botenya ba letlalo, le ho boloka mongobo oa letlalo le ts'ebetso ea thibelo ea stratum corneum ka ho eketsa acidic glycosaminoglycans le hyaluronic acid, e le hore letlalo le boloke ho tenyetseha ho hotle. Ho ka bonoa hore ho fokotseha ha ts'ebetso ea sistimi ea endocrine ea 'mele le hona ke e' ngoe ea lintlha tsa bohlokoa tse susumetsang mokhoa oa ho tsofala ha letlalo.
Ho fokotseha ha tlhahiso ea mali ho tsoa pituitary, adrenal, le gonads ho tlatsetsa liphetohong tse ikhethang 'meleng le letlalong le mekhoa ea boitšoaro e amanang le botsofali. Maemo a serum a 17β-estradiol, dehydroepiandrosterone, progesterone, hormone ea kholo, le hormone ea bona ea insulin growth factor (IGF)-I ea fokotseha ha lilemo li ntse li feta. Leha ho le joalo, maemo a hormone ea kholo le IGF-I serum ea banna a fokotsehile haholo, 'me ho fokotseha ha maemo a lihormone ho baahi ba bang ho ka etsahala boemong ba khale. Lihormone li ka ama sebopeho le ts'ebetso ea letlalo, ho kenella ha letlalo, pholiso, cortical lipogenesis, le metabolism ea letlalo. Kalafo ea ho nkela estrogen sebaka e ka thibela ho khaotsa ho ilela khoeli le botsofali ba letlalo ba tlhaho.
——”Epiphysiology ea Letlalo” Yinmao Dong, Laiji Ma, K'hemik'hale Indasteri ea Likhatiso
Ka hona, ha re ntse re hola, tlhokomelo ea rona maemong a letlalo e lokela ho eketseha butle-butle. Re ka sebelisa litsebi tse linglisebelisoa tsa tlhahlobo ea letlaloho shebella le ho bolela esale pele mohato oa letlalo, ho bolela esale pele mathata a letlalo esale pele, le ho sebetsana le 'ona ka mafolofolo.
Nako ea poso: Pherekhong-05-2023
