Ntho ea pele ea botsofali ba letlalo:
Mahlaseli a UV, ho etsa lifoto
70% ea botsofali ba letlalo bo tsoa ho photoaging
Mahlaseli a UV a ama collagen 'meleng ea rona, e bolokang letlalo le shebahala le le lecha. Haeba collagen e honyela, letlalo le tla be le fokotsitse elasticity, sagging, dullness, letlalo la letlalo le sa tšoaneng, hyperpigmentation, pigmentation le mathata a mang a letlalo.
Bophara ba letsatsi bo arotsoe ka UVA le UVB. Mahlaseli a UVB a na le maqhubu a makhutšoane 'me a ka chesa karolo e ka holimo ea letlalo la rona, a sitoa ho kenella ka hare ho letlalo; leha ho le joalo, mahlaseli a UVA a na le maqhubu a malelele 'me a ka phunyeletsa ka khalase le ho teba ka har'a letlalo, qetellong a fokolisa collagen' me a lebisa ho nts'etsopele ea wrinkles.
Ka mantsoe a bonolo, UVA e lebisa botsofaling, UVB e lebisa ho cheseng, 'me leseli la ultraviolet le ka senya DNA ea cellular, la fokotsa ts'ebetso ea fibroblast,' me synthesis ea collagen e thibetsoe, e lebisang ho phetoho ea lisele, botsofali le apoptosis. Kahoo, UV e hohle, ebang ke letsatsi kapa ho na le maru, o hloka ho etsa mosebetsi o motle oa ho sireletsa letsatsi.
Ntlha ea bobeli ea bohlokoa ka ho fetisisa ea ho tsofala ha letlalo
Li-radicals tsa mahala tsa oxidative
Lentsoe la bohlokoa bakeng sa li-radicals tsa mahala ke 'oksijene'. Re hema hoo e ka bang karolo ea 98 ho isa ho 99 lekholong ea oksijene nako le nako ha re hema; e sebelisetsoa ho chesa lijo tseo re li jang le ho lokolla limolek'hule tse nyenyane hore lisele tsa rona li sebetse, 'me e ntša matla a mangata ho etsa hore mesifa ea rona e sebetse.
Empa mohlomong 1% kapa 2% ea oksijene e khetha tsela e fapaneng le e kotsi, palo ena e nyenyane ea oksijene, e atisang ho bitsoa li-radicals tsa mahala, tse hlaselang lisele tsa rona. Ha nako e ntse e ea, tšenyo ena e ntse e bokellana ha nako e ntse e ea.
Ntho e hlokomelehang haholo ke matšoao a botsofali a hlahang letlalong. 'Mele ea rona e na le mokhoa oa ho itšireletsa o lokisang tšenyo e entsoeng liseleng tsa rona ka li-radicals tsa mahala, empa ha li-radicals tsa mahala li bokellana ka potlako ho feta lisele tsa' mele li ka li lokisang, letlalo lea tsofala butle-butle.
Setšoantšo se ka holimo ke lesela la 'mele oa rona, u ka bona ka ho hlaka hore karolo e ka holimo ea epidermis e lefifi' me karolo e ka tlaase ea letlalo e khanya hanyenyane, dermis ke moo re hlahisang collagen, 'me lisele tse hlahisang collagen li bitsoa fibroblasts, mechine e etsang collagen.
Li-fibroblasts tse bohareng ba setšoantšo ke li-fibroblasts, 'me tepo ea sekho e li pota-potileng ke collagen. Collagen e hlahisoa ke li-fibroblasts, 'me letlalo le lenyenyane ke marang-rang a collagen a mahlakoreng a mararo le a tiileng, a nang le li-fibroblasts tse hulang likhoele tsa collagen ka matla ho fa letlalo le lenyenyane sebopeho se tletseng le se boreleli.
'Me letlalo la khale, li-fibroblasts le khokahanyo ea collagen pakeng tsa ho arohana ha fibroblasts ea botsofali hangata li hana ho kenella ha collagen, ha nako e ntse e ea, letlalo le lona le ile la qala ho tsofala, sena ke seo re atisang ho se bua ka botsofali ba letlalo, re ka rarolla oxidation ea letlalo joang. letlalo le amohetse?
Ntle le ho ela hloko ho sireletsa letsatsi, re ka sebelisa tse ling tse nang le vithamine A, vithamine E, ferulic acid, resveratrol le lisebelisoa tse ling tsa lihlahisoa tsa tlhokomelo ea letlalo; hangata e ka boela ea ja litholoana le meroho e mebala e khanyang haholoanyane, e kang tamati, tamati e ruile ka lycopene.
E ka monya oksijene hantle 'me ea thibela khatello ea oxidative, u ka boela ua ja broccoli e ngata, broccoli e na le karolo e bitsoang oli ea mosetareta glycosides, ka mor'a ho kenngoa ha motsoako ona, li tla bolokoa letlalong, e le hore lisele tsa letlalo li khone ho itšireletsa. , litholoana tsena le meroho li ka khothalletsa lisele hore li se ke tsa tsofala.
Ntlha ea boraro ea bohlokoa ka ho fetisisa ea ho tsofala ha letlalo
Glyation ea letlalo
Glycation, ka mantsoe a setsebi, e bitsoa karabelo e seng enzymatic glycosylation kapa karabelo ea Melad. Molao-motheo ke hore ho fokotsa tsoekere ho tlama liprotheine ha ho se na li-enzyme; ho fokotsa tsoekere ho fetoha haholo ka liprotheine, 'me ho fokotsa tsoekere le liprotheine ho feta nako e telele ea oxidation, dehydrogenation, le rearrangement reaction, e leng se hlahisang tlhahiso ea lihlahisoa tsa ho qetela tsa glycosylation, kapa AGE ka nako e khutšoanyane.
AGE ke sehlopha sa litšila tse ke keng tsa fetoloa, tse 'mala o mosehla-sootho, tse amanang le likokoana-hloko tse sa tšabeng ho senyeha ha li-enzyme,' me ke tse ling tsa lisosa tse ka sehloohong tsa botsofali ba batho. Ha re ntse re tsofala, li-AGE li bokellana 'meleng, e leng se lebisang ho eketseha ha boima ba marako a ka hare a methapo ea mali, ho se leka-lekane ha metabolism ea masapo e lebisang ho osteoporosis, le ho timetsoa ha collagen le elastin fibers ka dermis e lebisang ho tsofala ha letlalo. Botsofali ba letlalo bo bakoang ke glycation bo akaretsoa ka polelo e le 'ngoe: tsoekere e senya liprotheine tse phetseng hantle' me e fetola liprotheine tse nyenyane hore e be likarolo tsa khale tsa protheine, e leng se lebisang ho tsofalang le ho lahleheloa ke elasticity ea collagen le likhoele tse elastic ka dermis.
Nako ea poso: May-29-2024
