Whitening Cosmetics lePigmentMetabolism
Melanin anabolism e arotsoe ka linako tse fapaneng.Bo-ramahlale ba lumela hore hoa khonahala ho ithuta li-agents tse tšoeu le ho sebetsa bakeng sa linako tse fapaneng tsa metabolism.
(1) Boemo ba pele ba melanin synthesis
① Ho kena-kenana le ho ngoloa le/kapa glycosylation ea tyrosinase;② Thibela balaoli ha ho thehoa tyrosinase;③ Taolo ea morao-rao ea tyrosinase.
(2) Melanin synthesis nako
Joalo ka enzyme ea bohlokoa le enzyme e fokotsang sekhahla bakeng sa synthesis ea melanin, tyrosinase inhibitors ke eona tataiso ea mantlha ea lipatlisiso le nts'etsopele hajoale.Kaha boholo ba lintho tse tšoeu tse kang phenol le catechol derivatives li tšoana ka sebopeho le tyrosine le dopa, li-whitening agents tse hlahlobiloeng hangata li khetholloa e le li-inhibitors tse se nang tlhōlisano kapa tsa tlhōlisano tsa tyrosinase.
(3) Mokhahlelo oa morao-rao oa motsoako oa melanin
① E thibela phetiso ea melanosome;lintho tse nang le serine protease inhibitory effect, tse kang rwj-50353, li qoba ka ho feletseng UBV-induced epidermal pigmentation;soybean trypsin inhibitor e na le phello e hlakileng ea bosoeu empa ha e na phello ho chefo ea lisele tsa pigment;Niacinamide, e ka sitisa phetiso ea melanocyte lipakeng tsa melanocyte le keratinocyte;② Ho hasana ha melanin le metabolism, α-hydroxy acid, mafura a mafura a mahala le retinoic acid, e susumelletsa ho tsosolosoa ha lisele le ho khothalletsa ho tlosoa ha melaninized keratinocyte.
Ke habohlokoa ho hlokomela hore lipatlisiso le tšebeliso ea lintho tse soeufatsang tse thehiloeng holim'a melanin metabolism ha lia lokela ho thibela le ho phekola li-plaque tsa senile.Kaha mochine oa ho thehoa ha senile plaque o amana le ho thehoa ha lipofuscin, lintho tse sebetsang tsa antioxidative li atisa ho sebelisoa ho lieha le ho khutlisetsa morao li-plaque tsa senile.
Nako ea poso: Jul-29-2022
